Product

Target/Type

Region

Pre-Clinical

IND

Phase I

Phase II

Pivotal/Phase III

NDA

NDA

1First-In-Class (Global Pioneer) Womens Health

(APL-1702)

Photodynamic drug-device combination product

Global

China

Europe

Cervical high grade squamous intraepithelial lesions (HSIL)   Partner:  

USA

Intend to submit a phase trial application to FDA

2First-In-Class (Global Pioneer) Urological Tumors

(APL-1202)

MetAP2

Global

China

NMIBC (First line monotherapy)   Partner:  

USA/China

Neoadjuvant therapy for MBIC in combo with tislelizumab

China

Last stage bladder cancer

APL-1501

MetAP

Global

Australia

(APL-1706)

Photosensitizer

China

Urological tumors   Partner:  

APLD 2304

Second generation blue light cystoscope

Global

NMIBC diagnosis and operation.   Partner:  

AT-014

Undisclosed

Global

Urological Tumors

AT-020

Undisclosed

Global

Multiple Solid Tumors

3First-In-Class (Global Pioneer) Breast Cancer and Gynecological Tumors

(APL-1202)

USP1

Global

Ovarian cancer, breast cancer, etc

AT-017

Undisclosed

Global

Breast cancer and others

AT-018

Undisclosed

Global

Ovarian cancer, breast cancer, etc

AT-021

Undisclosed

Global

Ovarian cancer, breast cancer, etc

4First-In-Class (Global Pioneer) Other Diseases

(APL-1401)

DBH

Global

USA/China

Breast cancer and other solid tumors

APL-2301

DBH

Global

Australia

Breast cancer and other solid tumors