Join Us

Are you the next “Asieris-er “on our team? Consider a career with Asieris Pharmaceutical (USA) Inc. let’s realize your potential together.

Who You Are

We are seeking applicants with the following attributes. The level of the position will depend on the qualifications of the selected candidate.

Description

We are seeking a highly motivated and experienced leader as the Head of Global Clinical Development (HGCD) based in China or the US. You will report to the Chief Development Officer (CDO) and work closely with the Leadership Team to define clinical and medical strategy, accountable for clinical projects. Responsible to build and strategize the investigational product development for one or more IPs, and steer with the responsible team members within the medical and clinical department, and cross-functional matrix, including Clinical Operation and CRO(s), responsible/guide for evaluation of emerging clinical trial data, data interpretation and data mining; ensure the conduct of studies according to GCPs and Departmental SOPs; oversee/guide in conducting literature searches and reviews, meta-analyses, and publishing data; oversee the review of clinical study entries; and lead the preparation of IND, NDA/BLA filing packages. 

•  Function as the medical and clinical lead for pre-registrational new drug development activities by evaluating new product potential and providing strategic recommendations with medical expertise.
• Lead and strategize the generation and implementation of clinical development plans, including TPP, study design, etc. for one or more IPs. 
• Supported by medical monitor function and other medical functional roles, guiding and organizing the team members for the planning, implementation, managing, and reporting of clinical trials and programs. Prepare, review, and approve clinical trial synopses and protocols, IB, and CSR. Review and approve Medical Monitoring Plans, Safety Plans, and Protocol Deviation Plans. Review SAPs and tables, LTF shells.
• Oversee/Guide data interpretation and data mining. Ensure that assigned studies are conducted according to GCPs and organizational SOPs Guide in conducting literature searches/reviews, meta-analyses, and publishing data Contribute to the preparation of IND/NDA medical sections. 
• Work closely with the internal team including clinical operation and CRO in the execution of trials and provide ongoing guidance to CRO for protocol-specific clinical issues, site problems, and recruitment strategies. 
• Meet and aim to exceed project expectations by recruiting, retaining, and developing a skilled, experienced, and motivated medical team. Manage and oversee appropriate resourcing of staff and staff assignments. Coach and provide guidance to the staff to be compliant. 
• Keep abreast with scientific knowledge of oncology drug clinical development and handles other tasks as required by Supervisor.

Requirements.

• Major in clinical medicine, with physician experience in clinical practice, in urology or gynecology would be a plus.
• The incumbent should have at least 10 + years of directly related pharmaceutical clinical research experience in both early and late phase studies, and MNC working experience is a plus.
• Experience in a leadership role within a matrixed, multifunctional R&D organization. 
• Demonstrated ability in strategic thinking and contingency planning with respect to pharmaceutical objectives
• Track record of exposure to the IND/NDA/BLA application and approval process.
• The incumbent must have demonstrated experience in clinical research, study trial management, clinical database maintenance, generation of research hypotheses, and publication and presentation of scientific information.
• Professionalism, objectiveness, critical thinking, evidence-based reasoning, and a positive outlook are of the utmost importance. Demonstrates the ability to work independently, analyze complex situations and proactively identify opportunities/issues; effectively solves problems that cross functional boundaries The abilities to work on a team, cooperate with colleagues, and effectively communicate with a diverse audience, at multiple levels, both inside and outside the company, are essential. Experience in people management, and matrix structure.
• Strong oral and written communication skills
• Good planning and tracking skills
• Demonstrated influence, negotiation, and conflict resolution skills, including the ability to influence without clear reporting authority.
• Good problem-solving skills for developing creative solutions.
• Job-related travel (domestic or international) is expected (max. 20%).

This position provides a unique opportunity to join and contribute to a fast-paced team, with a cutting-edge technology platform, and ample opportunity to grow with the company. 

Benefits at a Glance:

Asieris provides the following competitive benefits:

• Medical, Dental, Vision 
• Competitive Salary
• Company Paid time off, Sick leave, federal Holidays, Floating holidays.
• Retirement savings plan – 401(K) plan/employer Match  

If you have the drive, passion, and experience and are excited by this opportunity, and are ready to take your career to the next level then Apply Today!

Asieris Pharmaceuticals (688176.SH), founded in March 2010, is a global innovative pharma company specializing in new drugs for the treatment of genitourinary tumors and other major diseases. We strive to improve human health and help people live a more dignified life. We aim to become a global pharma leader that integrates R&D, manufacturing and commercialization in our areas of focus, as we provide best-in-class integrated diagnosis and treatment solutions for patients in China and worldwide.

Job Summary

The Head of Toxicology will be part of the Preclinical Development group supporting small molecule drug development at Asieris and will provide scientific expertise and leadership to the safety assessment of all Asieris programs. The candidate is expected to work in a highly collaborative team environment, playing a pivotal role at each stage of preclinical and early clinical development.

Essential Duties & Responsibilities

• Provide expert support, guidance and strategy on project safety assessments, with a specific focus on discovery & IND-stage small molecule projects.
• Serve as the key resource for toxicology, providing scientific knowledge and expertise to cross-functional project teams.
• Develop overall toxicology strategy and plans for lead candidates based on clinical development plan.
• Oversee preclinical toxicology studies at multiple external Contract Research Organizations (CRO).
• Design & execute investigative toxicology studies, based upon off & on-target safety profiles of the candidate drugs.
• Initiate appropriate processes for contract implementation, protocol development, and timeline optimization for toxicology studies.
  • Monitor toxicology studies for appropriate conduct, accuracy and timely execution; audit raw data for accuracy, review draft reports and finalize them as submission-ready documents for regulatory authorities.
• Proactively respond to study issues and resolve problems with study director.
• Internal and external communication
• Prepare verbal and written summaries for internal discussions. Work with the Preclinical Development team to develop optimal strategies to address specific safety issues and partner with project teams.
• Review and/or author toxicology and/or safety pharmacology sections of various regulatory documents (e.g., pre-IND briefing documents, INDs, IBs etc.) and ensure their regulatory compliance.
• Represent company at meetings with regulatory agencies.
• Present summary data to project teams and Asieris senior leadership.

Education & Experience

Ph.D. in Toxicology, Pathology, Physiology, Biochemistry or expertise in related biological science disciplines, with an emphasis on Oncology/Immunology is preferred. Ph.D.; Board Certification in Veterinary Anatomic Pathology (ACVP) and Board Certification in Toxicology (DABT) is highly desired.

Requirements

• 10+ years’ experience in toxicology small molecule drug development in Biotech/Pharma industry.
• Experience in filing multiple INDs is a must; experience in filing NDAs will be a plus.
• An in-depth understanding of toxicology and/or toxicologic pathology, and have experience designing and critically evaluating results of exploratory and GLP-compliant toxicology studies.
• Experience in supporting project team as toxicology representative.
• Excellent oral/written communication skills in English and Chinese.
• Additional expertise in specific toxicology areas, e.g. developmental & reproductive systems toxicology, endocrine systems toxicology, Toxico-kinetics/Toxico-dynamics simulation analyses etc., is a strong plus.

Compensation & Benefits

As a full-time employee of the Company, you will be eligible for company benefits：

• Flexible Working hours
• Paid Vacation
• 401k Plan
• Medical Insurance
• Year-end Performance Bonus
• Long Term Incentive Plans

Interested candidates please feel free to contact:

Human Resources – Ms. Cao Email: lxcao@asieris.cn

Are you the next “Asieris-er “in our team? Consider a career with Asieris Pharmaceutical (USA)
Inc. let’s realize your potential together.

Who You Are?

We are seeking an experienced and highly creative CO Director，Clinical Operation to manages and
develops Clinical Operation US team and participates in the planning and implementation of the
overall development strategy of Asieris clinical operations team. Who oversees and manages project
and site related activities, supervise, or develop action plans as needed to improve overall
operational efficiency，especially for US part. This CO-Director will ensure overall project meets
delivery requirements by collaborating with team members of differential functional groups. We are
seeking applicants with the following attributes. The level of the position will depend on the
qualifications of the selected candidate.

Description

• Responsible for team building, training, and management of US clinical operation team.
• Ensures the projects being executed on time, within budget and high quality，
particularly for US studies.
• Leads program managements，to drive efficiency, alignment and planning among the
projects.
• Ensures appropriate cross-functional input into the scope of work.
• Contributes to and has accountability for overall clinical operations strategy and performance
against key metrics.
• Maintains US expert, communicates with relevant review experts, clinical experts, and other
clinical research resources to develop the correct clinical implementation plan and ensures the
smooth running of clinical trials, particularly in US.
• Responsible for building up and maintaining good relationship with US sites，US KOLs,
and global vendors.

• Contributes to clinical operations and clinical trial sourcing strategy development and takes a
lead role in vendor governance.
• Contributes to SOP/process/system improvement，to ensure compliance with US FDA
and EMA requirements.
• Ensures clinical operations thinking, and activities are aligned with overall business direction
and priorities.
• Recommends best practices within clinical operations that if more broadly applied would benefit
Asieris as a whole.
• Maintains a working knowledge of, and assures compliance with, applicable ICH Guidelines, Good
Clinical Practices, Regulatory Agency requirements, and SOPs.
• Escalates issues to Asieris senior management team timely.
• Complete other tasks assigned by the leader.
• May serve as Clinical Operation Head when needed.

Requirements

• Bachelor's degree or above, majoring in clinical medicine, pharmacy, biology, etc. or related
majors.
• More than 10 years of experience in clinical trials of new drugs, preferably in multinational
companies or multicultural background.
• Minimum of 5 years of project management or/and people management experience.
• Excellent communication and coordination, resource integration, planning and team management
skills, strong leadership, performance, problem solving and contingency plan management skills.
• Well familiar with the operation mode and workflow of new drug clinical trials, GCP/ICH- GCP and
other related laws and regulations, as well as the development and status of clinical research.
• Proficiency in clinical project management, familiar with the operation mode of US registered
clinical studies and international multi-center clinical studies.
• Abundant industry resources, ability to coordinate clinical resources and solve various problems
in clinical research in a timely manner.
Core competencies
• Strong attention to detail
• Teamwork and collaboration
• Achieving results
• Good problem solver.
• Good interpersonal skills
• Well organized and can manage competing priorities.

Benefits at a Glance:

Asieris provides the following competitive benefits:

• Medical, Dental, Vision
• Competitive Salary
• Company Paid time off, Sick leave, federal Holidays, Floating holidays.

• Retirement savings plan – 401(K) plan/employer Match
• Flexible schedule
• Paid time off.
If you have the drive, passion, and experience, are excited by this opportunity, and are ready to
take your career to the next level, then Apply Today!

About US

Asieris Pharmaceuticals is a global clinical-stage pharmaceutical company specializing in
discovering new drugs for the treatment of genitourinary cancer and other major diseases,
headquartered in Shanghai, China. It was selected to be among China's top 30 innovative small
molecule drug discovery companies in October 2021.
Asieris is committed to creating a diverse environment and is proud to be an equal-opportunity
employer. All qualified applicants will receive consideration for employment without regard to
race, color, religion, gender, gender identity or expression, sexual orientation, national origin,
genetics, disability, age, or veteran status.

Are you the next “Asieris-er “in our team? Consider a career with Asieris Pharmaceutical (USA)
Inc. let’s realize your potential together.

Who You Are?

We are seeking applicants with the following attributes. The level of the position will depend on the qualifications of the selected candidate.

Description

Rooted in China, Asieris is poised for rapid global expansion and will be undertaking aggressive spin-off & M&A efforts to complement the organization's strong organic growth. Therefore, we are seeking a proven CFO with prior experience leading a high-growth, private-equity-backed healthcare company. The CFO, based in the US, will work closely with the CEO as a business partner, providing strong financial leadership and driving the company's overall growth strategy.

As the CFO, you will lead Asieris' finance team, supporting the entire organization and its business partners. Your primary responsibilities will include working with senior executives to establish financial and strategic goals for the company, developing financial and investing strategies to meet specific business objectives, and ensuring compliance with legal, regulatory, and securities reporting requirements.

Strategy Related:

• Advise the CEO on business development and strategic planning.
• Manage all short and long-term strategic financial objectives of the company, supporting the executive team with vital financial information and operational analytics, and driving a culture of accountability in managing the business.
• Lead Spin-off, M&A, and Joint Venture activities, providing financial insights, modeling, valuation, and risk analysis to facilitate decision-making.

External Affairs, especially in the Global Market:

• Lead fundraising efforts and collaborate with key stakeholders.

• Secure funding from various sources and develop relationships with investment banks as needed.
• Pursue funding and incentives from foundations, development banks, and government sources.
• Source, negotiate, and structure deals across business development, spin-off, M&A, and fundraising.

Internal Leadership:

• Mentor and guide the finance team on overall finance/accounting activities, including costing, budgeting, reporting, and internal controls to improve operating efficiency.

Requirements

• Strong strategic mindset in both finance and business areas.
• Experience with capital-intensive businesses and key investment targets, with the ability to manage relationships with investors, banks, and partners.
• Proven success in fundraising and closing significant deals.
• Knowledge of the investing ecosystem and key players.
• Strong finance-based analytical skills.
• 15+ years of finance experience, with multiple years as CFO of a private-equity-backed company.
• CPA or MBA preferred.

Benefits at a Glance:

Asieris provides the following competitive benefits:

• Medical, Dental, Vision
• Competitive Salary
• Company Paid time off, Sick leave, federal Holidays, Floating holidays.
• Retirement savings plan – 401(K) plan/employer Match

If you have the drive, passion, and experience, are excited by this opportunity, and are ready to
take your career to the next level, then Apply Today!

LOCATION(S): Palo Alto, CA, US or Shanghai/Beijing, China

About Asieris

Asieris Pharmaceuticals is a global clinical-stage pharmaceutical company specializing in
discovering new drugs for the treatment of genitourinary cancer and other major diseases,
headquartered in Shanghai, China. It was selected to be among China's top 30 innovative small
molecule drug discovery companies in October 2021.

Asieris is committed to creating a diverse environment and is proud to be an equal-opportunity
employer. All qualified applicants will receive consideration for employment without regard to
race, color, religion, gender, gender identity or expression, sexual orientation, national origin,
genetics, disability, age, or veteran status.

Are you the next “Asieris-er “in our team? Consider a career with Asieris Pharmaceutical (USA)
Inc. let’s realize your potential together.

Who You Are?

In our pursuit of global expansion, we are actively searching for a highly motivated and experienced leader from the United States to fill the role of Head of Business Development. This individual will oversee our global assets licensing activities.

Description

Reporting directly to the company's CEO, the Head of Business Development will be responsible for formulating and executing strategies that position Asieris as the preferred partner for potential collaborations and licensing agreements within the pharmaceutical and biotech industries.

Requirements

This position provides a unique opportunity to join and contribute to a fast-paced team, with a cutting-edge technology platform, and ample opportunity to grow with the company.

HOW YOU WILL MAKE AN IMPACT:

1. Strategy: Develop a business development strategy that aligns with the corporate vision and execute it effectively.
2. Sell and Buy: Structure, negotiate, and finalize out-licensing and in-licensing transactions to meet Asieris portfolio requirements.
3. Leadership: Lead deal projects, fostering collaboration across diverse teams including disciplines like discovery, CMC, Clinical Development, Regulatory Affairs, Finance, and Legal.
4. Growth: Generate company value through successful business outcomes and contribute to company expansion by building a skilled team

WHY WE VALUE YOU:

1. Global Perspective: You thrive in multicultural dynamics and embrace a global mindset.
2. Negotiation and Communication: You excel as a negotiator and an attentive listener, adept at steering conversations toward mutually beneficial results.
3. Sensitivity to Context: Your ability to gauge the situation and manage discussions to yield positive outcomes is exceptional.
4. Passion for Science: Your enthusiasm for science drives your work, and you're inherently self-motivated.
5. Organization: Your structured and well-organized approach enhances your effectiveness.

Desired Qualifications:

1. BD Experience: Possess 10+ years of experience in business development, preferably with experience on the sell side.
2. Travel: Be prepared for frequent travel, estimated at 50%.

Benefits Overview:

 At Asieris, we offer a comprehensive range of competitive benefits, including:

• Medical, Dental, and Vision Coverage
• Competitive Salary
• Company-Paid Time Off, Sick Leave, Federal Holidays, and Floating Holidays
• Retirement Savings Plan – 401(K) Plan with Employer % Match

If you have the drive, passion, and experience are excited by this opportunity, and are ready to take your career to the next level then Apply Today! Please attach a copy of the deal sheet along with your resume.

About Asieris

Asieris Pharmaceuticals is a global clinical-stage pharmaceutical company specializing in
discovering new drugs for the treatment of genitourinary cancer and other major diseases,
headquartered in Shanghai, China. It was selected to be among China's top 30 innovative small
molecule drug discovery companies in October 2021.

Asieris is committed to creating a diverse environment and is proud to be an equal-opportunity
employer. All qualified applicants will receive consideration for employment without regard to
race, color, religion, gender, gender identity or expression, sexual orientation, national origin,
genetics, disability, age, or veteran status.

Are you the next “Asieris-er “in our team? Consider a career with Asieris Pharmaceutical (USA)
Inc. let’s realize your potential together.

Who You Are?

We are seeking applicants with the following attributes. The level of the position will depend on the qualifications of the selected candidate.

Description

We are building a new Discovery Biology team in the San Francisco Bay area in USA. We are seeking an outstanding Research Associate II to join our new research team. The US team will focus on innovative research for the discovery of new drug targets and the development of therapeutics in Asieris’ niche indications.

Support proprietary biomedical discovery effort in the investigation of therapeutic drug candidates contributing to a wide range of treatments including genitourinary tumors and other related diseases. As directed, support research and development for clinical projects, using modern bioconjugation techniques and conjugate purification including FPLC and diafiltration; optimize conjugation conditions for DAR, recovery, and stability. Collaborate with chemists, biologists, and pharmacologists to interpret in vitro and in vivo assay results and propose means to advance programs. Set up, operate, and maintain laboratory instruments and equipment, monitor experiments, collect data and samples, make observations, and calculate and record results. Analyze organic substances. Conduct research, and assist in the research, including the collection of information and samples, such as blood and animal tissues. Use computers, computer-interfaced equipment, robotics, and high-technology industrial applications to perform experiments and examinations. Monitor and observe experiments, recording production and test data for evaluation by research personnel. Analyze experimental data and interpret results to write reports and summaries of findings. Provide technical support and services for scientists and engineers working on employer’s proprietary therapeutic drugs for disease and tumor treatment. Keep detailed logs of all work-related activities. Input data into databases. Isolate, identify and prepare specimens for examination. Set up, adjust, calibrate, clean, maintain, and troubleshoot laboratory and field equipment. Clean, maintain, and prepare supplies and work areas. Monitor laboratory work to ensure compliance with set standards. Place orders for laboratory equipment and supplies. Conduct biological, microbiological or biochemical tests and laboratory analyses to support the employer’s bioconjugate therapies and targeted drug delivery modalities. Implement clinical studies for project advancement. Generate processes and present high-quality data to the supervisor and immediate working group or project team. May examine and maintain laboratory animals for experimental needs. Ability to utilize qPCR technology, perform serological tests (ELISA), operate HPLC and LC-MS for molecule identification and characterization, and all other related quality control tests, etc.

Requirements

Requires a bachelor’s degree in Bioengineering, Chemical Biology, Biochemistry, Food Science, or a closely-related field, plus at least 5 years of post-degree, progressive work experience in performing microbiology lab tests, utilizing qPCR, ELISA, HPLC, and LC-MS.

This position provides a unique opportunity to join and contribute to a fast-paced team, with a cutting-edge technology platform, and ample opportunity to grow with the company.

Benefits at a Glance:

Asieris provides the following competitive benefits:

• Medical, Dental, Vision
• Competitive Salary
• Company Paid time off, Sick leave, federal Holidays, Floating holidays.
• Retirement savings plan – 401(K) plan/employer Match  

If you have the drive, passion, and experience are excited by this opportunity, and are ready to take your career to the next level then Apply Today!

Send resume to HR@asieris.com N. Sheng, Manager,

Asieris Pharmaceuticals USA Inc.,

2460 Embarcadero Way Suite B, Palo Alto, CA 94303.”

About Asieris

Asieris Pharmaceuticals is a global clinical-stage pharmaceutical company specializing in
discovering new drugs for the treatment of genitourinary cancer and other major diseases,
headquartered in Shanghai, China. It was selected to be among China's top 30 innovative small
molecule drug discovery companies in October 2021.

Asieris is committed to creating a diverse environment and is proud to be an equal-opportunity
employer. All qualified applicants will receive consideration for employment without regard to
race, color, religion, gender, gender identity or expression, sexual orientation, national origin,
genetics, disability, age, or veteran status.